Manuel van Gemmeren conducted his doctoral studies in the lab of Prof. Benjamin List (completed in 2014), followed by postdoctoral studies in the group of Prof. Rubén Martín. He led an independent research group at the University of Münster from 2016 to 2022, when he moved to Kiel University as professor for Organic Chemistry. Research in the van Gemmeren Lab focusses on the development of novel synthetic methods, typically based on C–H activation, that enable challenging transformations to proceed with catalyst-controlled reactivity and selectivity.
Catalysis; Organic Chemistry; C-H Activation; Transition Metals
Charge-controlled Pd catalysis enables the meta-C–H activation and olefination of arenes; A. Mondal, M. Diaz-Ruiz,+ F. Deufel,+ F. Maseras,* M. van Gemmeren* (+ = equal contribution); Chem. 2023, 9, 1004-1016. https://doi.org/10.1016/j.chempr.2022.12.019
Palladium-Catalyzed Nondirected Late-Stage C–H Deuteration of Arenes; M. Farizyan,+ A. Mondal,+ S. Mal,# F. Deufel,# M. van Gemmeren (+/# = equal contribution); J. Am. Chem. Soc. 2021, 143, 16370–16376. https://doi.org/10.1021/jacs.1c06474
Late-Stage β-C(sp3)–H Deuteration of Carboxylic Acids; A. Uttry, S. Mal, M. van Gemmeren; J. Am. Chem. Soc. 2021, 143, 10895-10901. https://doi.org/10.1021/jacs.1c06474
Mechanism of the Arene-Limited Nondirected C–H Activation of Arenes with Palladium; P. Wedi,+ M. Farizyan,+ K. Bergander, C. Mück-Lichtenfeld,* M. van Gemmeren (+ = equal contribution); Angew. Chem. Int. Ed. 2021, 60, 15641-15649. https://doi.org/10.1002/anie.202105092
H. Chen,+ P. Wedi,+ T. Meyer, G. Tavakoli, M. van Gemmeren, Dual Ligand-Enabled Non-Directed C–H Olefination of Arenes, Angew. Chem. Int. Ed. 2018, 57, 2497-2501. https://doi.org/10.1002/anie.201712235