Since our beginnings in studies of Allelopathy (1985) -study of the chemical language of plants- the group FQM-286, a pioneer in Europe, not only studies which specialized metabolites are involved in chemical interactions between plants and the ecosystem, but also in how their biological effects act and exert. Project full of new challenges through chemistry, the study of natural products, isolation, structural elucidation, partial and total synthesis, structure-activity relationship (SAR) studies, bioassays and recently nanoencapsulations and bioavailability, looking for applications in Agriculture and Pharmacology.
Isolation, functional evaluation, design and synthesis of drugs of natural origin.
Isolation, functional evaluation, design and synthesis of Agrochemicals of natural origin. Allelopathic studies in hihger plants and microorgnisms. Studioes of the structure-activity relationaships (SAR). Preparation of models of natural agrochemicals by partial and/ or total synthesis. Design of generalist and specific bioassys of phytotoxicity. Functional evaluation, design and preparation of functional foods
The group is an expert in extraction techniques for Natural Products (NP), conventional, natural and in supercritical conditions. In phytotoxicity, allelopathic, anti-parasitic plant, antibacterial, antifungal, cytotoxicity and bioavailability bioassay techniques. In structural elucidation techniques with IR, MS, UV, 1H and 13C NMR mono and two-dimensional. In separation techniques of NP by CC, FC, HPLC, UHPLC and CPC. In SAR and QSAR studies. In the design of interactions of Bioactive NP (BNP) with proteins via Docking studies. In partial and total synthesis of BNP. In BNP organic encapsulation: Polymer Nanoparticle, Supramolecular Polymer Micelle, Organic Nanotube, MOF, among others.