The group currently carries out research in three major research areas funded by regional and national agencies:
- Study of the control of infections produced by phytopathogenic fungi, especially Botrytis cinerea and in recent years Eutipa lata.
- Diterpenes as models in the design of new drugs
- Metabolomic study of marine microorganisms in the search for new drugs
ORCID ID: 0000-0002-8612-0593
Graduate in Chemistry from the University of Seville (1978), Doctorate from the University of Cadiz (UCA) in November 1984. Two postdoctoral stays: at the Institute of Natural Products of the CSIC, La Laguna (Tenerife), and at the University of Sussex, Brighton, UK, in 1985 and 1986, respectively. "Visiting professor" at the University of Oxford, 1990 and Reading, 2005.
Professor at the University of Cádiz 1987-2000. Professor of the Dept. of Organic Chemistry at the UCA, 2000-continue.
Author of more than 220 international publications and 7 book chapters. He has directed 27 doctoral theses. He has an H index of 40, and has six six-year periods of research.
- BIOTRANSFORMATIONS:
A) USING WHOLE MICROORGANISMS AS A WAY OF KNOWING THE METABOLIC PATHWAYS AND
B) AS A SYNTHETIC STRATEGY FOR OBTAINING ENANTIOMERICALLY PURE COMPOUNDS.
- DITERPENES AS A MODEL FOR NEW DRUGS
- BIOSYNTHETIC STUDIES INCORPORATING LABELLED INTERMEDIATES WITH STABLE ISOTOPES
- NEW DRUGS FROM MARINE MICROORGANISMS
- SYNTHESIS OF BIOACTIVE MOLECULES
- PHYTOPATHOGENIC FUNGAL TOXINS, EVALUATION OF THEIR INVOLVEMENT IN THE INFECTION PROCESS PRODUCED BY THE FUNGUS.
Representative publications
Link to extended list of publication
- Isolation and synthesis of secondary metabolites
- Structural characterization of bioactive molecules
- Synthesis of organic molecules.
- Genetic and molecular bases of the biosynthesis of bioactive molecules
- Chromatographic and spectroscopic techniques and organic synthesis.
- Molecular coupling studies (Docking) for drug design.
- Antibiotic and fungicide activity tests