Oscillations

Biorhythms underlie many aspects of our lives ensuring that all cellular processes occur in their optimal temporal niche. Molecular oscillators with circadian or ultradian (<24h) rhythms have been independently characterized in multiple organisms/cells and revealed to be crucial timekeeping mechanisms operating during DEVELOPMENT, AGEING AND DISEASE. Our group studies one such oscillator – the EMBRYO MOLECULAR CLOCK (EC) – which regulates the periodic formation of the vertebrate embryo axial skeleton precursors.