ORCID ID: 0000-0003-2897-6227
Born in a small village at Seville (Bollullos de la Mitación) in 1968, I obtained a degree in Biological Sciences at the University of Seville in 1992. I began my research formation in the Neuroscience Laboratory of the Department of Animal Physiology at the Biological Sciences School. I achieved my PhD in Biological Sciences at the University of Seville in 1997 with the defense of a research work carried out as the result of a collaboration between the Autonomous University of Madrid and the University of Seville. In 1998, I joined the University of Cadiz with a postdoctoral fellowship. Later, I obtained a position of University School Lecturer in 1999 that it became an University Lecturer in 2008. Finally, since 2016 I am Full Professor in the discipline of Human Physiology. I became an independent senior researcher at 2002 and in 2007 I founded, as the Chairman, the Neurodegeneration and Neurorepair Group (CTS597).
Neurotransmission, synaptic plasticity and synaptopathies
Physiopathology of motor systems
Mechanisms underlying neuron sensitization to degenerate
Identification and development of feasible therapeutic strategies for treatment of several motor pathologies and neurodegenerative diseases.
Representative publications
Link to extended list of publication
qRT-PCR and Western Blotting
Interferent RNA technology applied to in vitro specimens and in live animals.
Primary cultures of spinal cord motoneurons obtained from mouse embryos.
Electrophysiological recordings of field and unique cell in in vitro samples and in the entire animal
Calcium imaging in culture cells
Immunohistochemistry
Intracerebral administration of oligonucleotides and drugs
Microiontophoresis in the central nevous system
Transgenic model of ALS disease: SOD1G93A
Knockout mice: task1-/-, task3-/-, task1-/-/task3-/-