CTS150: Autoimmunity and Immune deficiencies

Submitted by francisco.grimaldi on Mon, 06/29/2020 - 15:59
University
University of Cadiz
Faculty/school/department
FACULTY OF MEDICINE/MEDICINE
Size of the team
number of researchers number of supporting staff number of PhD students
7
0
0
PI
PI name
JOSÉ ANTONIO GONZÁLEZ GIRÓN
PI email
joseantonio.giron@uca.es
PI bio

EDUCATION: Degree in Medicine from the Faculty of Medicine of the University of Granada, 1981  Doctorate in Medicine and Surgery (University of Granada, 1988) Master's Degree in Infectious Diseases from the University of Seville, 2013 Master's Degree in Clinical Unit Management from the University of Murcia, 2016
TEACHING ACTIVITY: University Professor, Department of Medicine, University of Cadiz, from 1991 to 2009. University Professor, Department of Medicine, University of Cadiz, from 2009 to present
Undergraduate teaching. Direction of Doctorate Programmes and participation in the Master of Biomedicine (University of Cadiz). Direction of 37 Doctoral Theses, six of them deserving of the Extraordinary Doctorate Award.  
Five (5) teaching five-year periods (last one granted 2016)
ASSISTANT ACTIVITY: University Professor linked to the Puerta del Mar University Hospital, Cadiz, since 1991. From 2013 Head of Internal Medicine Service. Accreditation excellent level by the Agency of Health Quality of Andalusia (2012)  
RESEARCH ACTIVITY:
Main research lines: analysis of inflammatory and immune activity in infectious diseases (mainly HIV and hepatitis C virus infection) and in autoimmune diseases  
Funding, obtained uninterruptedly from Public Agencies (mainly FIS and the Andalusian Regional Ministry of Health) since 1991; in a total of 14 projects I am a PI of the same: 7 FIS Projects, 1 FIPSE Project, 7 Projects from the Andalusian Regional Ministry of Health or Progreso y Salud Foundation.  
Publications: Up to April 2020, 130 articles have been published in journals collected by the JCR, with a number of citations received of 3163 and an h index of 28.  
Five (5) six-year periods of research (last granted 2018)  
ACTIVITY IN MANAGEMENT:
Vice-Dean of the Faculty of Medicine of the University of Cadiz, 1999-2005
Principal Investigator/Coordinator of the Research Group CTS 150 "Autoimmunity and Immunodeficiencies" of the Andalusian Plan for Research, Development and Innovation from 2000 to date  
Scientific Director of the Institute for Research and Innovation in Biomedicine of Cadiz from March 2017 to January 2020

Five (5) recognized regional complements (teaching, research, management) (last 2018)

Contact person and e-mail
Contact person
JOSÉ ANTONIO GONZÁLEZ GIRÓN
Contact person e-mail
joseantonio.giron@uca.es
WWW
https://cts150.uca.es/
Short description of research profile

HIV-HCV coinfection
Immune and inflammatory responses in infectious diseases
Immune and inflammatory responses in autoimmune diseases

Research area
MEDICAL AND HEALTH SCIENCES » Health sciences » (NN) INFECTIOUS DISEASES
Scientific Themes (keywords)
HIV; HCV; CYTOKINES; Chemokines; ADHESION MOLECULES
Publications

Representative publications

1. Antiretroviral therapy partially improves the abnormalities of dendritic cells and lymphoid and myeloid regulatory populations in recently infected HIV patients Márquez Coello M; Montes de Oca Arjona M; Martín Aspas A; Guerrero Sánchez F; Fernández Gutiérrez del Álamo C; Girón González JA Scientific Reports Springer Nature (2019) Vol: 9. Pgs: 11654- 
2. Bacterial translocation in HIV-infected patients with HCV cirrhosis: Implication in haemodynamic alterations and mortality. Montes de Oca, M, Marquez M, Soto MJ, Rodriguez-Ramos C, Terrón A, Vergara A, Arizcorreta A, Fernandez-Gutiérrez C, Girón-Gonzalez JA. J Acquir Immune Defic Syndr. 2011 Apr 15;56(5):420-7.
3. https://doi.org/10.1371/journal.pone.0066619Influence of genetic polymorphisms of tumor necrosis factor alpha and interleukin 10 genes on the risk of liver cirrhosis in HIV-HCV co-infected patients Corchado S, Márquez M, Montes de Oca M, Romero-Cores P, Fernández-Gutiérrez C, Girón-González JA. PLoS One. 2013 Jun 26;8(6):e66619.
4. Monocyte and lymphocyte activation and regulation in multiple sclerosis patients. Therapy effects González-Oria MC, Márquez-Coello M, Girón-Ortega JA, Argente J, Moya M, Girón-González JA J Neuroimmune Pharmacol. 2019 Sep;14(3):413-422
5. Soluble membrane receptors, interleukin 6, procalcitonin and C reactive protein as prognostic markers in patients with severe sepsis and septic shock Ríos-Toro JJ, Márquez-Coello M, García-Álvarez  JM, Martín-Aspas A, Rivera-Fernández R, Sáez de Benito A, Girón-González JA. PLoS One. 2017 Apr 5;12(4):e0175254.

Link to extended list of publication

https://cts150.uca.es/publicaciones-en-revistas/
Technology Expertise

Clinical research
Flow cytometry
Protein analysis
Nucleic acid analysis