Genetics, Functional Genomics and Biotechnology

Submitted by moderator_UBO on Mon, 04/06/2020 - 17:05
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Size of the team
number of researchers number of supporting staff number of PhD students
Composition of Joint Unit of Research, if relevant


PI name
Emmanuelle Genin
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Contact person
Contact person e-mail
Short description of research profile

The project of INSERM Unit 1078 is to enable a better understanding of the genetic and pathophysiological bases of some human genetic diseases, for example cystic fibrosis, hemochromatosis, hereditary chronic pancreatitis or some mitochondrial pathologies.

The ambition of our research project from gene to patient is to decipher the relationship between the structure of the genes and their function and between genotype and phenotype. To carry out these projects, Unit 1078 relies on:

  • genetics and molecular genomics approaches,
  • genetic epidemiological data,
  • expertise in transcription, splicing or in calcium signalling,
  • the development of original research models such as the baker's yeast.

The expected results are: an increasing knowledge concerning the molecular basis of the gene of interest and also the development of new diagnostic and therapeutical strategies in some model diseases.This project benefits from our expertise in SynNanoVect, a production platform for synthetic vectors and vectorization of biomolecules (Ministry of Research’s labelling and ISO 9001 certification), and in PurlProb, a proteomics support network. Both were created by and are hosted in our research unit.