immunology

Immunology and Lysosomal Storage Diseases group focuses on the field of Lipid Immunology, with a particular interest in the role of sphingolipids in modulating CD1-restricted T lymphocytes, including invariant Natural Killer T (iNKT) cells. A central aim of the group is to uncover how lipid-mediated immune modulation contributes to the pathophysiology of Lysosomal Storage Diseases, particularly sphingolipidoses such as Acid Sphingomyelinase Deficiency, Gaucher disease, and Fabry disease.

I am currently working on the immunologic features of human podocytes, as well as role of Klotho and NPP1 proteins in the course of diabetic nephropathy. Previously, I studied genetics and immunology of sarcoidosis and tuberculosis. I work with cell lines, I perform quantitative analyses of gene and protein expression. I also implement techniques like immunofluorescence and immunohistochemistry, and analyse glycolitic parametres of podocytes by measurement of extracellular acidification.