Professor of Psychobiology, University of Cádiz. Bachelor of Pharmacy (2000, University of Seville) and PhD from the University of Cádiz 2007. During this training period I did several research stays at the Faculty of Medicine-University of the Basque Country and the INSERM unit 288-University Pierre et Marie Curie de Paris, as well as in the R&D department of the Grünenthal GmbH (Germany). After defending my Doctoral Thesis in a European format (Extraordinary Prize, 2007), I joined Prof. McNaughton's research group (University of Cambridge) thanks to obtaining an EU Intra-European Marie Curie contract (FP7). Subsequently, I rejoined the University of Cádiz as a Temporary Substitute Professor and with a Marie Curie Reincorporation contract. I currently direct the Research Group in Neuropsychopharmacology and Psychobiology (CTS-510) and I am a Co-Principal Investigator of Group G18 of the Center for Biomedical Research Network of the Carlos III Health Institute in the Area of Mental Health, CIBER de Mental Health (CIBERSAM ). I am also part of the Institute of Research and Innovation in Biomedical Sciences of Cádiz (INiBICA).
STUDYING THE ACTION OF PSYCHO-DRUGS IN ANIMAL MODELS OF DEPRESSION AND PAIN IN KNOCKOUT MICE FOR THE MU-OPIOID RECEPTOR AND IN KNOCKOUT MICE FOR THE NFAT TRANSCRIPTION FACTOR .; STUDY THE COOPERATION OF SYNERGIC MECHANISMS BETWEEN OPIOIDS.
1) Animal models of disease: These include pharmacologic-, neurodevelopmental and genetically-induced alterations in rodents developing phenotypes resembling either individual or multiple symptoms associated with particular neurologic or psychiatric disorders (pain, depresssion, anxiety, schizophrenia, autism..)
2) Animal Behavior and Other In Vivo Assays: Behavioral tests in rodents, electrophysiology, modulation of gene expression in rodent brain (DREADD (Designer receptor exclusively activated by designer drugs))
3)Molecular and Cellular Biology: Quantitative RT-PCR system, Protein analysis (ELISA, Western blotting), Histopathology, Immunohistochemistry, Neuronal cultures derived from human olfactory neuroepithelium
Llorca-Torralba M, Suárez-Pereira I, Bravo L, Camarena-Delgado C,
Garcia-Partida JA, Mico JA, Berrocoso E
Biological Psychiatry (2019) Vol: 85. Pgs: 1021-1035
Jiménez-Sánchez L, Castañé A, Pérez-Caballero L, Grifoll-Escoda M, López-Gil
X, Campa L, Galofré M, Berrocoso E, Adell A
Cereb Cortex. 2016 Jun;26(6):2778-2789
Perez-Caballero L, Soto-Montenegro ML, Hidalgo-Figueroa M, Mico JA, Desco M,
Berrocoso E.
Brain Stimul. 2018 Nov - Dec;11(6):1348-1355
Torres-Sanchez S, Perez-Caballero L, Mico JA, Celada P, Berrocoso E
Brain Stimul. 2018 Jan - Feb;11(1):222-230
Berrocoso E, Rey-Brea R, Fernández-Arévalo M, Micó JA, Martín-Banderas L.
Nanomedicine. 2017 Nov;13(8):2623-2632