peptides

Human Cystatin C - conformational studies using NMR techniques and molecular dynamics
Study of the interaction of human cystine C with antibodies as potential amyloidosis inhibitors
Peptide antibiotics and peptidomimetics - design, synthesis, conformational studies
Peptides with pro-regenerative and neuroprotective properties - design, synthesis and physicochemical research
Design, synthesis and research of peptides with potential anti-cancer properties
Peptides and peptidomimetics in viral diseases

Main focus on biochemical characteristic of proteolytic enzymes using combinatorial chemistry methods. Design and synthesis of selective substrates of particular protease. Main interest: neutrophil proteases, diagnostic, molecular probes ect. Using our techniques we are able to characterized substrate specificity of any proteolytic enzyme. Also we are involoved in antimcrobial and immunostimulating peptides.