NMR structural studies

Understanding mechanisms of action of small proteins and peptides in biological systems. As a part of a large international (Poland, South Korea, USA, Argentina, France, Sweden) informal research group we participate in a project to develop what is called a coarse-grained (simplified) model of polypeptide chain called UNRES (UNited RESidues). (www.unres.pl)

Search and study of short peptide sequences having a defined spatial structure and showing the ability to catalyze chemical reactions.

Human Cystatin C - conformational studies using NMR techniques and molecular dynamics
Study of the interaction of human cystine C with antibodies as potential amyloidosis inhibitors
Peptide antibiotics and peptidomimetics - design, synthesis, conformational studies
Peptides with pro-regenerative and neuroprotective properties - design, synthesis and physicochemical research
Design, synthesis and research of peptides with potential anti-cancer properties
Peptides and peptidomimetics in viral diseases