I am currently working on the immunologic features of human podocytes, as well as role of Klotho and NPP1 proteins in the course of diabetic nephropathy. Previously, I studied genetics and immunology of sarcoidosis and tuberculosis. I work with cell lines, I perform quantitative analyses of gene and protein expression. I also implement techniques like immunofluorescence and immunohistochemistry, and analyse glycolitic parametres of podocytes by measurement of extracellular acidification.
1. Typiak M., Kulesza T., Rachubik P., Rogacka D., Audzeyenka I., Angielski S., Saleem M.A., Piwkowska A. Role of Klotho in hyperglycemia: its levels and effects on fibroblast growth factor receptors, glycolysis, and glomerular filtration. Int. J. Mol. Sci. 2021;22: 7867. doi.org/10.3390/ijms22157867.
https://www.mdpi.com/1422-0067/22/15/7867
2. Typiak M., Piwkowska A. Antiinflammatory Actions of Klotho: Implications for Therapy of Diabetic Nephropathy. Int. J. Mol. Sci. 2021;22(2): 956. doi:10.3390/ijms22020956.
https://www.mdpi.com/1422-0067/22/2/956
3. Typiak M., Rębała K., Haraś A., Skotarczak M., Słomiński J. M., Dubaniewicz A. Copy number variation of FCGR genes in etiopathogenesis of sarcoidosis. PLoS ONE 2017;12(5): e0177194.
https://journals.plos.org/plosone/article?id=10.1371/journal.pone.0177194
4. Typiak M., Rebala K., Dudziak M., Dubaniewicz A. Polymorphism of FCGR2A, FCGR2C and FCGR3B genes in the etiopathogenesis of sarcoidosis. Adv Exp Med Biol 2016;905: 57-68.
https://link.springer.com/chapter/10.1007/5584_2015_193
5. Typiak M.J., Rębała K., Dudziak M., Dubaniewicz A. Polymorphism of FCGR3A gene in sarcoidosis. Hum Immunol 2014;75: 283-288.
https://www.sciencedirect.com/science/article/abs/pii/S0198885914000810?via%3Dihub