(DA) BIOPHYSICS

The main objectives of our research are to describe the mechanisms of action of a wide variety of toxic substances, to search for protective compounds and to reveal their mechanisms of action, to develop new effective methods to modulate the activity of drugs with particular emphasis on drugs used in anticancer therapy and antibiotics.

Development of bacterial growth/inactivation models. Study of modes of antibacterial action of metallic nanoparticles through experimental probing and modelling. Characterization of nanoparticles. Atomic force microscopy and spectroscopy of different cell types. Study of the transport of different membrane species within a membrane. Modeling and simulating membrane diffusion. Understanding an interplay between all the physical effects on the length and time scales of the living cell.