Chemical sciences

• radionuclides determination (Po, Pb, Gd, Ra, Cs, U, Th, Pu, Am) in food and diet supplements as well as in environmental samples;
• speciation, distribution and accumulation of radioisotopes in living organisms and their radiological effects;
• food as radioactive elements source;
• Chernobyl accident and other radiation events impact on the radioactive contamination

Structural studies of glycans and glycoconjugates isolated from various natural sources: gram negative bacteria, gram positive bacteria, fungi, plants and human tissues.

Main focus on biochemical characteristic of proteolytic enzymes using combinatorial chemistry methods. Design and synthesis of selective substrates of particular protease. Main interest: neutrophil proteases, diagnostic, molecular probes ect. Using our techniques we are able to characterized substrate specificity of any proteolytic enzyme. Also we are involoved in antimcrobial and immunostimulating peptides.

LBCM has developed a recognized scientific specialty in marine biofilms study (organized populations of microorganisms growing on surfaces). Using a variety of tools and approaches that combines genetics, analytical chemistry and cell physiology, this laboratory studies the interactions between living organisms and abiotics, and promotes the biotechnological developments that emerge from them.

Environmental Analytical Chemistry,

Separation and microextraction techniques,

Trace elements, Green Techniques,

Environmental water pollution and environmental impacts

1) Advanced Electron Microscopy for Nanomaterials characterization

2) Nanoscale analysis of nano materials for Heterogeneous Catalysis

3) Nanoscale analysis of nano materials for sensors

4) Nanoscale analysis of nano materials for Biomedicine and biotechnology

5) Development and optimization of novel methodologies for the 2D and 3D characterization of Nano and Bio materials by Advanced Transmission and Scanning Transmission Electron Microscopy

6) Electron Tomography of Nanostructured Materials

- Design of sensor molecules and optical sensors in the determination of metals.

- Ecotoxicological effects caused by the presence of metallic nanomaterials in aquatic systems and possible biomarkers sensitive to these emerging pollutants.

- Study of the potential of plant and food residues as metal biosorbents.

- Assessment of metal contamination in aquatic ecosystems: speciation, bioaccumulation, ecotoxicological effects and bioindicators of metallic contamination.

- BIOTRANSFORMATIONS:

A) USING WHOLE MICROORGANISMS AS A WAY OF KNOWING THE METABOLIC PATHWAYS AND

B) AS A SYNTHETIC STRATEGY FOR OBTAINING ENANTIOMERICALLY PURE COMPOUNDS.

- DITERPENES AS A MODEL FOR NEW DRUGS

- BIOSYNTHETIC STUDIES INCORPORATING LABELLED INTERMEDIATES WITH STABLE ISOTOPES

- NEW DRUGS FROM MARINE MICROORGANISMS

- SYNTHESIS OF BIOACTIVE MOLECULES

- PHYTOPATHOGENIC FUNGAL TOXINS, EVALUATION OF THEIR INVOLVEMENT IN THE INFECTION PROCESS PRODUCED BY THE FUNGUS.

Isolation, functional evaluation, design and synthesis of drugs of natural origin.

Isolation, functional evaluation, design and synthesis of Agrochemicals of natural origin. Allelopathic studies in hihger plants and microorgnisms. Studioes of the structure-activity relationaships (SAR). Preparation of models of natural agrochemicals by partial and/ or total synthesis. Design of generalist and specific bioassys of phytotoxicity. Functional evaluation, design and preparation of functional foods

Application of chemometric techniques to electroanalytical and spectroscopic data.

Electrochemical and structural characterization of nanomaterials and ceramic and composite materials.

Contribution of different analytical techniques to the resolution of real problems.

Quality control and food security.

Development of new electrode (nano)materials.